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pentobarbital will minimize the extent or effect of darunavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.Contraindicated (one)pentobarbital will lower the extent or effect of doravirine by affecting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will lessen the level or effect of finasteride by